CANBERRA — In a landmark decision that could transform the landscape of public health in Australia, the Pharmaceutical Benefits Advisory Committee (PBAC) has officially recommended Wegovy (semaglutide) for inclusion on the Pharmaceutical Benefits Scheme (PBS).

The recommendation, announced following the committee’s November meeting, specifically targets adults living with established cardiovascular disease and obesity. If finalized by the Health Minister, the move will provide subsidized, life-saving access to a medication that currently costs patients upwards of $400 per month on the private market.


Targeted Subsidies: Who Qualifies?

Recognizing the immense budgetary pressure of GLP-1 medications, the PBAC has established strict eligibility criteria. The goal is to prioritize “high-need” patients where the clinical benefit—specifically the reduction of heart attacks and strokes—is most significant.

Clinical Eligibility Criteria

To qualify for the subsidized rate (which would bring the cost down to a standard co-payment of approximately $31.60, or $7.70 for concession holders), patients must meet the following requirements:

  • Medical History: Must have an “established cardiovascular disease,” defined as a prior heart attack, stroke, or symptomatic peripheral arterial disease.
  • The BMI Threshold: A Body Mass Index (BMI) of 35 kg/m² or higher for the general population.

Ethnic Risk Adjustments

In a move praised by health equity advocates, the PBAC has lowered the BMI threshold for specific high-risk ethnic groups. Access will be granted at a BMI of 32.5 kg/m² or higher for:

  • Aboriginal and Torres Strait Islander peoples
  • Individuals of Asian ethnicity

This adjustment accounts for clinical data showing that these populations often face higher risks of metabolic complications and cardiovascular events at lower BMI levels compared to those of European descent.


The Science of GLP-1: Why Wegovy?

Wegovy is a glucagon-like peptide-1 (GLP-1) receptor agonist. It works by mimicking a natural hormone that targets areas of the brain that regulate appetite and food intake.

While its “sibling” drug, Ozempic, has been available on the PBS for years, it is strictly restricted to the treatment of Type 2 diabetes. Wegovy’s recommendation marks the first time a dedicated weight-management medication of this class has been cleared for subsidy based on its ability to reduce secondary cardiovascular events.

The Obesity Epidemic by the Numbers

The PBAC’s decision comes as Australia grapples with a burgeoning health crisis. According to the latest Australian Institute of Health and Welfare (AIHW) statistics:

  • 67% of Australian adults are overweight or obese.
  • 31% of the population (approximately 6.3 million people) are classified as obese.
  • Obesity is a leading risk factor for Type 2 diabetes, 22 types of cancer, and heart disease, costing the Australian economy an estimated $11.8 billion annually in direct and indirect costs.

Balancing the Budget: The Minister’s Dilemma

While the recommendation is a victory for patients, it presents a significant financial challenge for Health Minister Mark Butler. GLP-1 drugs are notoriously expensive to subsidize due to the sheer volume of potential claimants.

In March 2025, Minister Butler requested formal advice from the PBAC on how to ensure “equitable and sustainable” access to these drugs. The current recommendation for Wegovy is seen as a compromise: it offers relief to the most vulnerable (those already suffering from heart disease) while excluding millions of others who are obese but do not yet have established cardiovascular complications.

“The PBAC must balance clinical evidence against the long-term sustainability of the PBS,” noted Dr. David Henry of Bond University. “Scaling these subsidies without long-term data on sustained use and weight regain remains a complexity for the government.”


Implications for Health Equity

The Royal Australian College of General Practitioners (RACGP) has long called for better access to weight-management tools for underserved populations. Historically, obesity treatment has been a “user-pays” system, where only the wealthy could afford the latest pharmaceutical interventions.

By including specific BMI thresholds for Asian and Indigenous Australians, the PBAC is addressing “health inequities”—ensuring that those statistically at higher risk of death from heart disease aren’t barred from treatment by their bank accounts.


Future Outlook: Tirzepatide and Beyond

The Wegovy recommendation sets a crucial precedent. Other pharmaceutical giants are watching closely, including Eli Lilly, the manufacturer of Zepbound (tirzepatide). Previous applications for these drugs were rejected due to “inadequate justification of cost-effectiveness.” The shift toward a “cardiovascular-risk-first” model appears to be the key that finally unlocked the PBAC’s approval.

What Happens Next?

  1. Ministerial Approval: Minister Mark Butler must sign off on the recommendation.
  2. Price Negotiation: The government will negotiate a confidential price with the manufacturer, Novo Nordisk.
  3. Supply Chain Check: Rollout will depend on global supply. Australia has faced significant shortages of semaglutide (Ozempic) throughout 2024 and 2025 due to unprecedented global demand.

Long-Term Concerns

Experts continue to monitor “GLP-1 sustainability.” Data suggests that many patients regain weight once the medication is stopped, leading to questions about whether the PBS will be required to fund these drugs for a patient’s entire lifetime. Additionally, gastrointestinal side effects remain a common reason for treatment discontinuation.


Summary Table: Wegovy PBS Recommendation (Dec 2025)

CategoryEligibility Requirement
Primary ConditionEstablished Cardiovascular Disease (Heart Attack/Stroke)
General BMI Threshold≥35 kg/m²
High-Risk Ethnic Threshold≥32.5 kg/m² (Asian, Indigenous Australian)
Projected Cost (Subsidized)~$31.60 per month
Current Private Cost$400 – $600 per month
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